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On a recent episode of the popular show ESPN Sports Science, poker pros David Oppenheim and Ali Eslami participated in a few experiments to see what kind of changes the human body underwent during a poker match.

If you’re unfamiliar with the show, Sports Science basically looks at certain aspects of professional sports and measures them in a scientific way. In the past everything from Chad OchoCinco’s ability to cut on a dime, to the power generated by a tackle has been measured. In the poker episode the Sports Science team performed several experiments, including hooking the players up to a polygraph test, measuring their pupil dilation, and had a body language expert on hand to read the polygraph and look for physical tells.

All-in-all the conclusions come to at the end of the episode are pretty much what you would have expected: That is to say that physiological changes do occur –Ali Eslami stopped breathing for a moment when he bluffed and David Oppenheim sweated more when bluffing—but they are extremely hard to detect, even for experts, and as every poker player knows the same tell can apply to both a bluff and a monster hand! So tread with caution.

Another interesting revelation was the difference in the muscles used when a player is genuinely smiling as opposed to a fake smile. According to the show genuine smiles use muscles that left the lips up, where a false smile pulls the lips outwards.

To watch ESPN Sports Science check your local listings for airtimes in your area.